Abdulla El Madani
About Dr. Abdulla
Al-Zaytoonah Private University of Jordan (henceforth, Al-Zaytoonah) was established in 1993 after receiving its license and general accreditation by Decision No. 848 on March 6, 1993. Instruction began on September 6, 1993, and since then Al-Zaytoonah has witnessed ... Read more
Vision
There are 300 faculty members of various ranks distributed among the six faculties of the University, and 80 teaching and research assistants and lab technicians. In addition, there are 210 administrative employees and 260 workers.

Blog

Patent

Patent

Local Anaesthetic Medical Device – Brighton University-2002 Registration

Fluid Delivery Device – Pub No: WO/2001/083018 – International PCT/GB2001/002039

FLUID DELIVERY DEVICE

Intraurethral procedures are painful to the patient and it is therefore highly desirable to anaesthetise the urethra before insertion of surgical instruments or medical devices. Current clinical practice is to anaesthetise locally the urethra during intraurethral procedures using a commercially available topical preparation which may contain, for instance, lignocaine hydrochloride 2%.

Despite the use of topical anaesthetic agents, patients still experience considerable pain and discomfort during intraurethral procedures. Indeed, research suggests that attempting to anaesthetise the urethra using the methods of current clinical practice may have little advantage over using a plain lubricating gel (“Prospective, randomized, double-blind study comparing lignocaine gel and plain lubricating gel in relieving pain during flexible cystoscopy”, S Choong et al British Journal of Urology [1997] vol. 80, 69-71).

The current clinical practice is to deliver the anaesthetic agent with a common syringe. Such a crude delivery method has many limitations because of the nature of the urinary tract. The most severe pain during intraurethral instrumentation is experienced when a surgical instrument is in the region of the membranous and prostatic segments of the urethra.

However, to reach these areas, the anaesthetic agent has to pass beyond the external (voluntary) urinary sphincter which normally exerts a pressure of about 80 cm of water into the urethra. The sphincter may contract further if the patient is in pain thereby further increasing the pressure. The sphincter thus impedes the path of the anaesthetic fluid which will tend to be forced back out around the sides of the syringe nozzle.

WO/2001/083018 FLUID DELIVERY DEVICE – WIPO

University of Brighton

Huxley Building

Lewes Road

Brighton BN2 4GJ

UK

Publications

 Publications:

 

Taghizadeh, A.K, El Mandini, A, Gard, P.R, Li, C.Y, Thomas, P.J and Denyer S.P (2006) When does it hurt? Pain during flexible cystoscopy in men Urologia Intenationalis, 76 (4). pp. 301-303. ISSN 0042-1138

 

Taghizadeh, A.K., El Madani, A., GARD, PAUL, Li, C.-Y., Thomas, P.J. and Denyer, S.P. (2006) when does it hurt? Pain during flexible cystoscopy in men Urology Internationalis, 76 (4). pp. 301-303. ISSN 0042-1138

1. Urol Int. 2006; 76(4):301-3.

 

When does it hurt? Pain during flexible cystoscopy in men.

 

Taghizadeh AK(1), El Madani A, Gard PR, Li CY, Thomas PJ, Denyer SP.

 

Author information:

(1)Department of Urology, Royal Sussex County Hospital, Brighton, UK.

a.taghizadeh@ukonline.co.uk

 

INTRODUCTION: In this observational study, pain was measured continuously in men undergoing flexible cystoscopy, in order to help to identify which parts of the procedure were the most painful.

PATIENTS AND METHODS: Men who were to undergo flexible cystoscopy were recruited.

Pain was measured continuously throughout flexible cystoscopy by asking the subject to squeeze a pressure-sensing rubber bulb in proportion to the amount of discomfort experienced giving a score of 0-10.

RESULTS: The most painful part of the procedure was as the cystoscopy passed through the membranous urethra with a median pain score of 2.82. The initial lidocaine administration gives a median pain score of 0.84. The other parts of the cystoscopy produced median scores of between 0.14 and 0.33. The difference in the pain scores was significant (p = 0.03). There was no statistically significant difference in the pain scores between those who were having their first cystoscopy and those who were having repeat cystoscopy. The subjects’ age did not influence the degree of pain experienced.

CONCLUSION: This study gives further understanding of how pain is experienced during flexible cystoscopy. It may help explain why previous studies have not reached a clear consensus on the value of lidocaine during flexible cystoscopy.

Research Interests

Research Interests      

 

Research Interests in Pharmaceutical include the development of drug formulation and evaluation of novel drug delivery and technologies, models of drug delivery to the testing of their biocompatibility and pharmaceutical processing

 

Rheology of gels and drug controlled release.

Local Anaesthetics and drug delivery during flexible cystoscopy in men urology applications.

Development of medical devices.

Pain evaluation devices.

In Vitro methods to assess biocompatibility and functional performance of drug delivery.

Drug Formation and technology applications.

Antimicrobial drug control in urology catheters applications.

Development of multi filters techniques to control the toxicity in tobacco smoking.

Contact

Please don’t hesitate to contact me for more information about my work.

Tel: +962-6-4291511
Fax: +962-6-4291432

No more, where are you going?

Go back to top or use the menu to your left to navigate.

Thanks for downloading!

Top