Ghassan Abu Sheikha

Visiting Research Scholar                                                                            June 2013 – Aug 2013

College of Pharmacy and Pharmaceutical Sciences

University of Toledo

Toledo, OH

USA

Dean                                                                                                               July 2011 – present

Professor of Medicinal Chemistry

Faculty of Pharmacy

Al-Zaytoonah University

Amman, Jordan

Dean                                                                                                               Sept 2005 – July 2011

Associate Professor of Medicinal Chemistry

Faculty of Pharmacy

Al-Zaytoonah University

Amman, Jordan

Associate Professor of Medicinal Chemistry                                              Aug 2004 – Aug 2005           College of Pharmacy,

King Khalid University

Abha, Saudi Arabia

Associate Professor of Medicinal Chemistry                                              Feb 2004 – Aug 2004        Faculty of Pharmacy

Philadelphia University

Amman, Jordan

Dean                                                                                                               Feb 2003 – Oct 2003

Associate Professor of Medicinal Chemistry                                             

Faculty of Pharmacy

Applied Science University

Amman, Jordan

Dean

Assistant Professor of Medicinal Chemistry                                               July 2002 – Feb 2003                Faculty of Pharmacy

Applied Science University

Amman, Jordan

Deputy Dean                                                       

Assistant Professor of Medicinal Chemistry                                               Aug 2001 – Oct 2001                Faculty of Pharmacy

Applied Science University

Amman, Jordan

Assistant Professor of Medicinal Chemistry                                               Sept 1998 – Feb 2003    Faculty of Pharmacy

Applied Science University

Amman, Jordan

Assistant Research Professor                                                                       July1997– April 1998 Faculty of Pharmacy

Camerino University

Camerino, Italy

1. Kamal Sweidan, Jörn Engelmann, Walid Abu Rayyan, Dima Sabbah, Musa Abu Zarga, Tariq Al-Qirim,Yusuf Al-Hiari, Ghassan Abu Sheikha, Ghassan Shattat. Synthesis and Preliminary Biological Evaluation of New Heterocyclic Carboxamide Models. LDDD, 2014, accepted and in press.

http://benthamscience.com/journal/abstracts.php?journalID=lddd&articleID=126527

2. Al-Qirim, Tariq; Shattat, Ghassan; Abu Sheikha, Ghassan; Sweidan, Kamal; Al-Hiari, Yusuf; Jarab, Anan. Synthesis and in vivo antihyperlipidemic activity of new series of N-(4-benzoylphenyl)-2-furamide derivatives Triton-WR-1339-Induced hyperlipidemic Rats. Drug Research, 2014, accepted and in press.

http://www.unboundmedicine.com/medline/citation/24848001/

3. Manal AL-Najdawi, Yusuf Al-Hiari, Tariq Al-Qirim, Ghassan Shattat, Mohammad Al-Zweri and Ghassan Abu Sheikha.  Synthesis and Pharmacological Evaluation of Novel Unsubstituted Indole-Anthraquinone Carboxamides Derivatives as Potent Anti-hyperlipidemic Agents. Z. Naturforsch, 69c. 2014, 21-28.

http://www.znaturforsch.com/ac/v69c/69c0021.htm

4. Reema Abu Khalaf, Ghassan Abu Sheikha, Mahmoud Al-Sha’er, Mutasem Taha. Design, Synthesis and Biological Evaluation of N⁴-Sulfonamido-Succinamic, Phthalamic, Acrylic and Benzoyl Acetic Acid Derivatives as Potential DPP IV Inhibitors. The Open Medicinal Chemistry Journal. 2013, 7, 39-48.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866624/

5. Ghassan Shattat, Tariq Al-Qirim, Ghassan Abu Sheikha, Yusuf Al-Hiari, Kamal Sweidan, Rania Al-Qirim, Suhair Hikmat, Lama Hamadneh, Sameer Al-kouz  The Pharmacological Effects of Novel 5-Fluoro-N-(9,10-dihydro-9,10-dioxoanthracen-8-yl)-1H-indole-2-carboxamide Derivatives on Plasma Lipid الملف الشخصي of Triton-WR-1339-Induced Wistar Rats. Journal of Enzyme Inhibition and Medicinal Chemistry. 2013, 28(4), 863-869.

http://informahealthcare.com/doi/abs/10.3109/14756366.2012.692085

6. Tariq Al-Qirim, Ghassan Shattat, Kamal Sweidan, Waseem El-Huneidi, Ghassan Abu Sheikha, Reema Abu Khalafand Suhair Hikmat. In vivo Antihyperlipidemic Activity of New Series of N- (benzoylphenyl) and N-(acetylphenyl)-1-benzofuran-2- carboxamides in Rats. Archiv der Pharmazie (Weinheim, Germany), 2012, 345(5), 401-406.

7. Reema Abu Khalaf, Ghassan Abu Sheikha, Ghadeer Albadawi, and Mutasem O. Taha. Design, synthesis and biological evaluation of sulfonic acid ester and benzenesulfonamide derivatives as potential CETP inhibitors. Medicinal Chemistry Research, 2012, 21(11), 3669-3680. http://link.springer.com/article/10.1007%2Fs00044-011-9917-5#page-1

8. Yusuf Al-Hiari, Ghassan Shattat, Tariq Al-Qirim, Waseem El-Huneidi, Ghassan Abu Sheikha and Suhair Hikmat. Antihyperlipidemic Properties of Novel N-(Benzoylphenyl)-5-substituted-1H-indole-2-carboxamides in     Triton WR-1339-Induced Hyperlipidemic Rats. Molecules 2011, 16(10): 8292-8304.

http://www.mdpi.com/1420-3049/16/10/8292

9. Rana M. OBAIDAT, Ammar BADER , Wafa AL-RAJAB , Ghassan ABU SHEIKHA  , Aiman A. OBAIDAT. Preparation of Mucoadhesive Oral Patches Containing Tetracycline Hydrochloride and Carvacrol for Treatment of Local Mouth Bacterial Infections and Candidiasis. Sci. Pharm. 2011; 79: 197–212.

http://www.ncbi.nlm.nih.gov/pubmed/21617783

10. Ghassan Abu Sheikha, Mahmoud A. Al-Sha’er, Mutasem O. Taha. Some Sulfonamide drugs inhibit ATP-ase activity of heat shock protein 90: investigation by docking   simulation and experimental validation. Journal of Enzyme Inhibition and Medicinal Chemistry, 26, 603-609, 2011.

http://informahealthcare.com/doi/abs/10.3109/14756366.2010.541394

11. Ghassan Abu Sheikha, Buthina Hussin, Yusuf Al-Hiari, Tariq Al-Qirim and Ghassan Shattat. Synthesis of Benzothiophene Carboxamide Derivatives and Their Pharmacological Evaluation as Potent Antihypertriglyceridemic Agents in Rats.  Z. Naturforsch, 66c, 93-103, 2011.

http://www.ncbi.nlm.nih.gov/pubmed/21630582

12. Ghassan Shattat, Rania Al-Qirim, Yusuf Al-Hiari, Ghassan Abu sheikha, Tariq Al-Qirim, Waseem El-Huneidi and Moyad Shahwan. Synthesis and      Anti-Hyperlipidemic Evaluation of N-(Benzoylphenyl)-5-fluoro-1H-indole-2-carboxamide Derivatives in Triton WR-1339-Induced Hyperlipidemic Rats. Molecules 15, 5840-5849, 2010.

http://www.mdpi.com/1420-3049/15/9/5840

13. Ghassan Abu Sheikha, Reema Abu Khalaf, Areej Melhem and Ghadeer Albadawi. Design, Synthesis, and Biological Evaluation of Benzylamino-Methanone Based Cholestryl Ester Transfer Protein Inhibitors. Molecules 15, 5721-5733, 2010.

http://www.mdpi.com/1420-3049/15/8/5721

 For more publications please see C.V

Advanced Medicinal Chemistry (For Ms. Students)

Advanced Organic Pharmaceutical Chemistry (For Ms. Students)

Research Methodologies (For Ms. Students)  

                                       Organic Pharmaceutical Chemistry I

                                       Organic Pharmaceutical Chemistry II

Medicinal Chemistry I

Medicinal Chemistry II

Medicinal Chemistry III

Drug Design

Principles in Pharmaceutical Research

Practical Pharmaceutical Research Workshop

Organic Pharmaceutical Chemistry Lab I

Organic Pharmaceutical Chemistry Lab II

Medicinal Chemistry Lab II

Medicinal Chemistry Lab III

Principles in Pharmaceutical Research Lab