Background
EDUCATIONAL BACKGROUND:
- Ph.D. of Medicinal Chemistry & Drug Discovery, with an average of (3.97 out of 4.00) rating Excellent, Faculty of Pharmacy, University of Jordan, August 2009, Amman-Jordan.
Thesis title : Discovery of new cholesteryl ester transfer protein (CETP) inhibitors via ligand-based pharmacophore modeling and QSAR analysis and subsequent hit optimization.
- M.Sc. of Pharmaceutical sciences, with an overall GPA of (4.00 out of 4.00) rating Excellent , Faculty of Pharmacy, University of Jordan, September 2002, Amman-Jordan.
Thesis title : Synthesis and microbiological evaluation of some novel derivatives of some natural and synthetic polymers.
- B.Sc. of Pharmacy, with an overeall GPA of (85.3 %) rating Excellent, Faculty of Pharmacy, University of Jordan, June 1994, Amman-Jordan.
- General secondary education certificate (science section) with final average (93.9 %), July 1989, Sukeina Secondary School for Girls , Amman-Jordan.
GRANTS:
- Design, Synthesis, and Biological Evaluation of New DPP-IV Inhibitors, 2019-2020. Research funds supported by the Deanship of Scientific Research of Al-Zaytoonah University of Jordan, 23,000 JD.
- Research funds supported by the Deanship of Scientific Research of Al-Zaytoonah University of Jordan from 2017-2019, (36,000 JD). Project title: Design, Synthesis, and Biological Evaluation of a New Series of CETP Inhibitors.
- Research funds supported by the Deanship of Scientific Research of Al-Zaytoonah University of Jordan from 2015-2016, (38,100 JD). Project title: 3-Benzylamino-Benzamides: Design, Synthesis, and Biological Evaluation as Novel CETP Inhibitors.
- Research funds supported by the Deanship of Scientific Research of Al-Zaytoonah University of Jordan from 2014-2016, (108,000 JD). Project Title: Design, Synthesis, and Biological Evaluation of PI3Ks Inhibitors.
- Research funds supported by the Deanship of Scientific Research of Al-Zaytoonah University of Jordan from 2012-2014, (130,000 JD). Project Title: Design, synthesis and biological evaluation of a new series of potential CETP inhibitors.
- Research funds supported by the Deanship of Scientific Research of Al-Zaytoonah University of Jordan from 2008-2011.
- Research funds supported by the Deanship of Scientific Research of University of Jordan from 2007-2009.
SCIENTIFIC, ACADEMIC, and ADMINISTRATIVE ACTIVITIES:
- Reviewer and Referee for Medicinal Chemistry Research Journal.
- Reviewer and Referee for Molecules Journal.
- Reviewer and Referee for Journal of Molecular Graphics and Modelling.
- Reviewer and Referee for Letters in Drug Design & Discovery Journal.
- Reviewer and Referee for Journal of Modern Medicinal Chemistry.
- Reviewer and Referee for the Arabian Journal of Chemistry.
- Reviewer and Referee for Analytical Methods Journal.
- Reviewer and Referee for Medicinal Chemistry Journal.
- Reviewer and Referee for the Jordan Journal of Pharmaceutical Sciences.
- Reviewer and Referee for the World Journal of Microbiology and Biotechnology.
- Editorial board for the VRI Biological Medicinal Chemistry Journal.
MEMBERSHIP IN THE FOLLOWING COMMITTEES:
• University Scientific Research Committee.
• Faculty Scientific Research Committee.
• Faculty Higher Education Committee.
• Department Council.
• Member of Jordan Pharmaceutical Association since July, 1994. Amman-Jordan Tel. 5665320
• Hold Jordanian Pharmacy Practice issued by Ministry of Health, July, 1994. Amman-Jordan.
AWARDS:
Distinguished Researcher Award at Al-Zaytoonah University of Jordan in 19th October 2012.
Tuesday 10, 2016
Reema Abu Khalaf, Dalal Masalha, Dima Sabbah.
Current Computer-Aided Drug Design, 2019, 15, Ahead of Print.
Abstract: Background: Lately, diabetes has become a main health concern for millions of people around the world. Objective: Dipeptidyl peptidase-IV (DPP-IV) enzyme inhibitors, gliptins, are a novel modality for treatment of type II diabetes by enhancing the activity of incretin hormones. Methods: Herein, quantum–polarized ligand docking and ligand-based pharmacophore modeling investigations were performed. Three novel 3,8-disubsituted-6-phenyl phenanthridine derivatives 3-5 have been designed, synthesized and characterized. Results: These compounds were proven to have DPP-IV inhibitory activity where compound 5 displayed the best activity with a % inhibition of 45.4 at 100 μM concentration. Conclusion: The computational results of this research shows that the size of the scaffold and the nature of the substitutions hinders the binding, suggesting future structural simplification.
Sunday 18, 2015
11/2018- up to date:
Professor of Medicinal Chemistry, Drug Discovery and Instrumental Analysis. Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman-Jordan.
11/2014- 11/2018:
Associate Professor of Medicinal Chemistry, Drug Discovery and Instrumental Analysis. Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman-Jordan.
11/2009- 11/2014:
Assistant Professor of Medicinal Chemistry, Drug Discovery and Instrumental Analysis. Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman-Jordan.
10/2011- 10/2017:
Assistant Dean for Quality Assurance, Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman-Jordan.
2003- 2009:
Lecturer of Medicinal Chemistry, Pharmaceutical Analytical Chemistry & Instrumental Analysis at Faculty of Pharmacy, Al-Zaytoonah University of Jordan, Amman-Jordan.
Sunday 18, 2015
- Asma Jumah (M.S), Examiner. Design, Synthesis, and Biological Evaluation of N-Substituted-4-Hydroxy-8-Methoxy-2-Quinolone-3-Carboxamides as PI3Kα Inhibitors, 2018/2019. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Maha Awad (M.S), Supervisor. Shiff’s Bases: Synthesis, characterization, in vitro and in vivo biological evaluation as DPP-IV inhibitors, 2018/2019. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Amani Abu Sa’ed (M.S), Supervisor. Synthesis, characterization and biological evaluation of novel benzamides as CETP inhibitors, 2018/2019. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Ebtisam Al-Warafi (M.S), Supervisor. Piperazine sulfonamides: synthesis, characterization, and in vitro biological evaluation as potential DPP-IV inhibitors, 2018/2019. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Bara’a Al-Nawaiseh (M.S), Supervisor. Halogenated benzamides: synthesis and in vitro study as potential cholesteryl ester transfer protein (CETP) inhibitors, 2018/2019. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Sara Mefleh (M.S), Supervisor. Synthesis and biological evaluation of novel hydrazone derivatives as potential dipeptidyl peptidase-4 inhibitors, 2017/2018. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Shorouq Al-Qazaqi (M.S), Supervisor. Synthesis and Biological Evaluation of sulfonamide derivatives as new DPPIV inhibitors, 2017/2018. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Maram Abu Rezeq (M.S), Supervisor. Synthesis, spectroscopic characterization and biological evaluation of phenanthridine derivatives as potential DPP-IV inhibitors, 2017/2018. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Hazar Ahmad Yousef (M.S), Examiner. Structure-based modeling to search for new anaplastic lymphoma kinase (ALK) inhibitors, 2017. Faculty of Pharmacy/Applied Science University.
- Shaima’a Emad Hasan (M.S), Supervisor. Design, Synthesis, and Biological Evaluation of N-Substituted-4-Hydroxy-6-Methyl-2-Quinolone-3-Carboxamides as PI3Kα Inhibitors, 2016/2017. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Samer M. Abu-Joudah (M.S), Examiner. The use of structure-based modeling and in vitro assay for the exploration of new spleen tyrosine kinase inhibitors, 2017. Faculty of Pharmacy/Applied Science University.
- Ala’a abuRezeq (M.S), Examiner. Development and Optimization of Oleogels and Bigels as إلى الأعلىical Drug Delivery Systems for Periodontitis, 1/2017. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Haya Abu Jarad (M.S), Supervisor. Synthesis and Biological Evaluation of Piperazine Derivatives as DPP-IV Inhibitors, 2016/2017. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Nisreen Sha’aban Hamadah (M.S), Examiner. Optimization of 4-hydroxy-2-quinolone-3-carboxamide core nucleus targeting PI3Kα inhibition, 2016/2017. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Haneen Muneer Abuzaid (M.S), Examiner. Design, Synthesis and In Vivo Biological Evaluation of Imidazole-5-Carboxamide Derivatives as Lipoprotein Lipase Activators, 8/2016. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Ameerah Said Hasan Ibrahim (M.S), Examiner. Optimization and Synthesis of Benzoin Derivatives as PI3Kα Inhibitors, 6/2016. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Fatima Mahmoud Al-Tarawneh (M.S), Examiner. Design, Synthesis, and Biological Evaluation of Benzoin Schiff’s Bases as Antitumor Agents, 5/2016. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Sajeda Ali Salah (M.S), Examiner. Discovery of new Gyrase B inhibitors via structure based modeling, 2016. Faculty of Pharmacy/Applied Science University.
- Nisreen Nazmi ”Haj Ahmad” (M.S), Supervisor. Synthesis and Antihyperlipidemic Properties of Novel N-(4-Benzoylphenyl) Pyrrole-2-Carboxamide Derivatives, 1/2016. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Areej Khalil Nasserallah (M.S), Supervisor. Synthesis and Biological Evaluation of Benzylamino Benzamide Derivatives as Potential CETP Inhibitors, 2015/2016. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Sarah Al-Rawashdeh (M.S), Supervisor. Fluorinated Benzamides: Design, Synthesis and Biological Evaluation as Potential CETP Inhibitors, 2014/2015. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Dalal Al-Masalha (M.S), Supervisor. Phenanthridines: Design, Synthesis and Biological Evaluation as Potential DPP-IV Inhibitors, 2014/2015. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Musaab Saada (M.S), Supervisor. Pharmacophore-Based Screening and Identification of Novel Phosphoinosited 3-Kinase (PI3Kα) Inhibitors, 2013/2014. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Bayan Salah Hishmah (M.S), Examiner. Design, Synthesis and Biological Evaluation of Novel PI3K Alpha Inhibitors, 12/2014. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Hamadah Abd-ElAziz (M.S), Supervisor. Synthesis and biological evaluation of substituted fluorinated alkyloxy benzylamino benzenamide as potential CETP inhibitors, 2013/2014. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Zainab Ali Jarekji (M.S), Supervisor. Design, Synthesis and Biological Evaluation of a New Series of Potential DPP IV Inhibitors, 2012/2013. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
- Mohammed Alhindi (M.S), Supervisor. Design, Synthesis and Biological Evaluation of a New Series of Potential CETP Inhibitors, 2012/2013. Faculty of Pharmacy/Al-Zaytoonah University of Jordan.
Sunday 18, 2015
Sewidan N, Abu Khalaf Reema, Mohammad H, Hammad W; In Vitro Studies on Selected Jordanian Plants as Dipeptidyl Peptidase-IV Inhibitors for Management of Diabetes Mellitus, Iranian Journal of Pharmaceutical Research, 2019, Accepted.
- Abu Khalaf Reema, Masalha D, Sabbah D; DPP-IV Inhibitory Phenanthridines: Ligand, Structure-Based Design, and Synthesis, Current Computer-Aided Drug Design, 2019, Ahead of Print.
- Sabbah D, Ibrahim A, Talib W, Alqaisi K, Sweidan K, Bardaweel S, Abu Sheikha G, Zhong H, Al-Shalabi E, Abu Khalaf Reema, Mubarak M; Ligand-Based Drug Design: Synthesis and Biological Evaluation of Substituted Benzoin Derivatives as Potential Antitumor Agents, Medicinal Chemistry, 2018, Ahead of Print.
- Abu Khalaf Reema, Sabbah D, Al-Shalabi E, Al-Sheikh I, Albadawi G, Abu Sheikha G; Synthesis, Structural Characterization and Docking Studies of Sulfamoyl-Phenyl Acid Esters as Dipeptidyl Peptidase-IV Inhibitors, Current Computer-Aided Drug Design, 14 (2), 2018, 142-151.
- Sabbah D, Al-Tarawneh F, Talib W, Sweidan K, Bardaweel S, Al-Shalabi E, Zhong H, Abu Sheikha G, Abu Khalaf Reema, Mubarak M; Benzoin Schiff Bases: Design, Synthesis, and Biological Evaluation as Potential Antitumor Agents, Medicinal Chemistry, 14 (7), 2018, 695 – 708.
- Abu Sheikha G, Bkhaitan M, Kalloush H, Hamadneh L, Abu Khalaf Reema, Al-Qirim T, Al-Hiari Y; Synthesis of Novel Benzimidazole-2-Carboxamide Derivatives and In Vivo Antihyperlipidemic Activity Evaluation, Chemical and Pharmaceutical Bulletin, 66 (4), 2018, 423-426.
- Sabbah D, Hishmah B, Sweidan K, Bardaweel S, AlDamen M, Zhong H, Abu Khalaf Reema, Ibrahim A, Al-Qirim T, Abu Sheikha G, Mubarak M; Structure-Based Design: Synthesis, X-Ray Crystallography, and Biological Evaluation of N-Substituted-4-Hydroxy-2-Quinolone-3-Carboxamides as Potential PI3Kα Inhibitors, Anti-Cancer Agents in Medicinal Chemistry, 18 (2), 2018, 263-276.
- Abu Khalaf Reema, Sabbah D, Al-Shalabi E, Bishtawi S, Albadawi G, Abu Sheikha G; Synthesis, biological evaluation and molecular modeling study of substituted benzyl benzamides as CETP inhibitors, Archiv der Pharmazie, 350 (12), 2017, 1-14.
- Abu Khalaf Reema, Abd El-Aziz H, Sabbah D, Albadawi G, Abu Sheikha G; CETP Inhibitory Activity of Chlorobenzyl Benzamides: QPLD Docking, Pharmacophore Mapping, and Synthesis, Letters in Drug Design & Discovery, 14 (12), 2017, 1391-1400.
- Hikmat S, Al-Qirim T, Alkabbani D, Shattat G, Abu Sheikha G, Sabbah D, Abu Khalaf Reema, Al-hiari Y; Synthesis and in vivo anti-hyperlipidemic activity of novel N-benzoylphenyl-2-furamide derivatives in Wistar rats, Tropical Journal of Pharmaceutical Research, 16 (1), 2017, 193-201.
- Abu Khalaf Reema, Al-Rawashdeh S, Sabbah D, Abu Sheikha G; Molecular Docking and Pharmacophore Modeling Studies of Fluorinated Benzamides as Potential CETP Inhibitors, Medicinal Chemistry, 13 (3), 2017, 239-253.
- Abu Khalaf Reema; Exploring Natural Products as a Source for Antidiabetic Lead Compounds and Possible Lead Optimization, Current إلى الأعلىics in Medicinal Chemistry, 16 (23), 2016, 2549-2561.
- Shattat G, Abusheikha G, Al-Qirim T, Huwaitat R, El-Huneidi W, Abu Khalaf Reema, Al-Hiari Y, Jasim S, Hamadneh L; Novel Pyrrole Derivatives as Potent lipid-Lowering Agents in Triton-WR-1339-Induced Hyperlipidemic Rats, Latin American Journal of Pharmacy, 34 (6), 2015, 1258-1264.
- Sabbah D, Saada M, Abu Khalaf Reema, Bardaweel S, Sweidan K, Al-Qirim T, Al-Zughier A, Abdel Halim H, Abu Sheikha G; Molecular modeling based approach, synthesis, and cytotoxic activity of novel benzoin derivatives targeting phosphoinostide 3-kinase (PI3Kα), Bioorganic & medicinal Chemistry Letters, 25 (16), 2015, 3120-3124.
- Abu Khalaf Reema, Jarekji Z, Al-Qirim T, Sabbah D, Shattat G; Pharmacophore modeling and molecular docking studies of acridines as potential DPP-IV inhibitors, Canadian Journal of Chemistry, 93 (7), 2015, 721-729.
- Abu Khalaf Reema, AbdulaAM, Mubarak MS, Taha MO; Tryptophan and thiosemicarbazide derivatives: design, synthesis, and biological evaluation as potential β-D-galactosidase and β-D-glucosidase inhibitors, Medicinal Chemistry Research, 24 (6), 2015, 2529-2550.
- Abu Khalaf Reema, Abu Sheikha G, Al-Sha’er M, Taha M; Design, Synthesis and Biological Evaluation of N4-Sulfonamido Succinamic, Phthalamic, Acrylic and Benzoyl Acetic Acid Derivatives as Potential DPP IV Inhibitors, The Open Medicinal Chemistry Journal, 7, 2013, 39-48.
- Al-Qirim T, Shattat G, Sweidan K, El-Huneidi W, Abu Sheikha G, Abu Khalaf Reema, Hikmat S; In Vivo Antihyperlipidemic Activity of New Series of N-(Benzoylphenyl) and N-(Acetylphenyl)-1-benzofuran-2-carboxamides in Rats, Archiv der Pharmazie, 345 (5), 2012, 401-406.
- Abu Khalaf Reema, Abu Sheikha G, Al-Sha’er M, Ghadeer Albadawi, Taha MO; Design, synthesis and biological evaluation of sulfonic acid ester and benzenesulfonamide derivatives as potential CETP inhibitors, Medicinal Chemistry Research, 21 (11), 2012, 3669-3680.
- Taha MO, Qandil AM, Al-Haraznah T, Abu Khalaf Reema, Zalloum H,Al-Bakri AG; Discovery of New Anti Fungal Leads via Pharmacophore Modeling and QSAR Analysis of Fungal N-Myristoyl Transferase Inhibitors followed by In Silico Screening, Chemical Biology and Drug Design, 78 (3), 2011, 391-407.
- Abu Khalaf Reema, AbdulaAM, Mubarak MS, Taha MO; Discovery of New β-D-Glucosidase Inhibitors via Pharmacophore Modeling and QSAR Analysis Followed by In Silico Screening, Journal of Molecular Modeling, 17 (3), 2011, 443-464.
- AbdulaAM, Abu Khalaf Reema, Mubarak MS, Taha MO; Discovery of New β-D-Galactosidase Inhibitors via Pharmacophore Modeling and QSAR Analysis Followed by In Silico Screening, Journal of Computational Chemistry, 32 (3), 2011, 463-482.
- Abu Sheikha G, Abu Khalaf Reema, Areej Melhem, Ghadeer Albadawi; Design, synthesis, and biological evaluation of new benzylamino methanone based cholesteryl ester transfer protein inhibitors, Molecules, 15 (8), 2010, 5721-5733.
- Abu Khalaf Reema, Abu Sheikha G, Bustanji Y, Taha MO; Discovery of new cholesteryl ester transfer protein inhibitors via ligand-based pharmacophore modeling and QSAR analysis followed by synthetic exploration, European Journal of Medicinal Chemistry, 45 (4), 2010, 1598-1617.
Published Books:
Reema Abu Khalaf, Alhusban A, Al-Shalabi E, Al-Sheikh I, Sabbah D.
Chapter: Isolation and Structure Elucidation of Bioactive Polyphenols,
In Book: Studies in Natural Product Chemistry (Bioactive Natural Products), Volume 63
Editor: Atta-Ur-Rahman, Elsevier Science Publishers – Amsterdam, the Netherlands, 2019.
Published Abstracts:
- Reema Abu Khalaf, Dima Sabbah, Eveen Al-Shalabi, Iyad Al-Sheikh, Ghadeer Albadawi, Ghassan Abu Sheikha; Oral Presentation: Synthesis, Structural Characterization and Docking Studies of Sulfamoyl-Phenyl Acid Esters as Dipeptidyl Peptidase-IV Inhibitors, 4th Pharmaceutical Chemistry Conference, June 27-28 2019, Amsterdam, Netherlands.
- Ghassan Abu Sheikha, Dima Sabbah, Shaima’ Hasan, Reema Abu Khalaf, Sanaa` Bardaweel, Kamal Sweidan, Eveen Al-Shalabi, Tariq Al-Qirim, Wamidh Talib, Haizhen A. Zhong; Poster Presentation: Phosphatidylinositol 3-Kinase Alpha (PI3Kα) Enzyme in Cancer Progression: Design, Synthesis, and Biological Evaluation of Novel Molecules Targeting the PI3Kα as Anticancer Agents, Stem Cells and Cancer, Gordon Research Conference, March 24-29 2019, Ventura Beach Marriott, Ventura, CA, United States.
- Nisreen Hamadeh, Dima Sabbah, Reema Abu Khalaf, Wamidh Talib; Oral Presentation: Structure-Based Design: Synthesis and Biological Evaluation of N-Substituted-4-Hydroxy-6-Nitro-2-Quinolone-3-Carboxamides as Potential PI3Kα Inhibitors, ASU-Pharmacy Fourth Symposium “Recent Trends in Postgraduate Research”, January 5-6th 2019, Amman, Jordan.
- Reema Abu Khalaf, D Sabbah, E Al-Shalabi, S Bishtawi, G Albadawi, G Abu Sheikha; Oral presentation: Synthesis, biological evaluation and molecular modeling study of substituted benzyl benzamides as CETP inhibitors, BIT’s 16th Annual Congress of International Drug Discovery Science and Technology (IDDST), August 16-19, 2018, Boston, USA.
- Ghassan Abu Sheikha, Haneen AbuZaid, Hanin Kalloush, Suhair Hikmat, Lama Hamadneh, Samah Ata, Dima Sabbah, Majdi Bkhaitan, Reema Abu Khalaf, Ghassan Shattat, Tariq Al-Qirim, Kamal Sweidan, and Yusuf Al-Hiari; Poster Presentation: Synthesis of Novel Benzimidazole-2-Carboxamide and Imidazoles-5-Carboxamide Derivatives and In Vivo Antihyperlipidemic Activity Evaluation. Ligand Recognition and Molecular Gating. Gordon Research Conference, March 4-9, 2018, Ventura Beach Marriott, Ventura, CA.
- Dima Sabbah, Bayan Hishmah, Kamal Sweidan, Sanaa Bardaweel, Murad AlDamen, Haizhen A. Zhong, Reema Abu Khalaf, Ameerah (Hasan Ibrahim), Tariq Al-Qirim, Ghassan Abu Sheikha, Mohammad S. Mubarak; Oral Presentation: Pharmacophore Based-Design of Phosphoinositide-3-Kinase (PI3Kα) Inhibitors, Al-Zaytoonah University of Jordan and the University of Toledo International Pharmaceutical Conference (ZTIPC 2017) “New Horizons in Pharmaceutical Research”, November 29-30, 2017, Amman, Jordan.
- Fatima Al-Tarawneh, Dima Sabbah, Wamidh Talib, Kamal Sweidan, Sanaa Bardaweel, Eveen Al-Shalabi, Haizhen A. Zhong, Ghassan Abu Sheikha, Reema Abu Khalaf, Mohammad S. Mubarak; Poster Presentation: Structure-Based Design, Synthesis, and Biological Evaluation of Benzoin Schiff Bases as Potential Antitumor Agents, Al-Zaytoonah University of Jordan and the University of Toledo International Pharmaceutical Conference (ZTIPC 2017) “New Horizons in Pharmaceutical Research”, November 29-30, 2017, Amman, Jordan.
- Reema Abu Khalaf, Sarah Al-Rawashdeh, Dima Sabbah, Ghassan Abu Sheikha; Oral Presentation: Fluorinated Benzamides: Molecular Docking and Pharmacophore Modeling Studies Targeting CETP Inhibition, BIT’s 15th Annual Congress of International Drug Discovery Science and Technology (IDDST), July 25-27, 2017, Osaka, Japan.
- Abd El-Aziz H, Reema Abu Khalaf, Sabbah D, Albadawi G, Abu Sheikha G; Poster Presentation: CETP Inhibitory Activity of Chlorobenzyl Benzamides: QPLD Docking, Pharmacophore Mapping, and Synthesis, Drug Discovery & Therapy World Congress, July 10-13, 2017, Boston, MA, USA.
- Ameerah (Hasan Ibrahim), Bayan Hishmah, Dima Sabbah, Kamal Sweidan, Sanaa Bardaweel, Murad AlDamen, Reema Abu Khalaf, Haizhen A. Zhong, Tariq Al-Qirim, Ghassan Abu Sheikha; Poster Presentation: N-Substituted-4-Hydroxy-2-Quinolone-3-Carboxamides as Potential PI3Kα, ASU-Pharmacy Third Symposium “Recent Trends in Postgraduate Research”, April 15-16, 2017, Amman, Jordan. The Poster is awarded the Third Place in Postgraduate Poster Competition.
- Ghassan Abu Sheikha, Dima Sabbah, Bayan Hishmah, Kamal Sweidan, Sanaa Bardaweel, Murad AlDamen, Haizhen A. Zhong, Ameerah (Hasan Ibrahim), Reema Abu Khalaf, Tariq Al-Qirim; Poster Presentation: Structure-Based Drug Design, Synthesis, X-ray Crystallography, and Biological Evaluation of N-Substituted-4-Hydroxy-2-Quinolone-3-Carboxamides as PI3Kα Inhibitors, Mammalian DNA Repair, Gordon Research Conference: Frontiers of Mammalian Genomic Stability in Human Health, February 19-24, 2017, Ventura, CA, USA.
- Dima Sabbah, Musaab Saada, Reema Abu Khalaf, Sanaa Bardaweel, Kamal Sweidan, Tariq Al-Qirim, Amani Al-Zughier, Heba Abdel Halim, Ghassan Abu Sheikha, Poster Presentation: Structure-Based Drug Design, Synthesis, and Biological Evaluation of Benzoin Analogues as otential PI3Kα Inhibitors, The University of Jordan School of Pharmacy, The 4th international Conference & the 2nd Conference of the Association of Faculties of Pharmacy at Jordanian Universities” Excellence in Pharmacy Education & Research: A Quality Approach”, October 25-27, 2016, Amman, Jordan.
- Musaab Saada, Dima Sabbah, Reema Abu Khalaf, Sanaa Bardaweel, Kamal Sweidan, Tariq Al-Qirim, Amani Al-Zughier, Heba Abdel Halim, Ghassan Abu Sheikha; Poster Presentation: Structure-Based Drug Design, Synthesis, and Biological Evaluation of Novel Benzoin Derivatives as anticancer agents. ASU-Pharmacy Second Symposium ”Recent Trends in Postgraduate Research”, December 5-6, 2015, Amman, Jordan.
- Reema Abu Khalaf, Ghassan Abu Sheikha; Oral Presentation: Synthesis and Biological Evaluation of Substituted Fluorinated Benzylamino Benzamides as Potential CETP Inhibitors, Al-Zaytoonah University of Jordan and the University of Toledo International Pharmaceutical Conference (ZTIPC 2015) “Frontiers in the pharmaceutical sciences and pharmacy practice: A global perspective”, October 21-23, 2015, Amman, Jordan.
- Dima Sabbah, Musaab Saada, Reema Abu Khalaf, Sanaa Bardaweel, Kamal Sweidan, Tariq Al-Qirim, Amani Al-Zughier, Heba Abdel Halim, Ghassan Abu Sheikha; Oral Presentation: From Hit to Lead: Structure-Based Drug Design, Synthesis, and Biological Evaluation of Novel Benzoin Derivatives as PI3Kα Inhibitors, Al-Zaytoonah University of Jordan and the University of Toledo International Pharmaceutical Conference (ZTIPC 2015) “Frontiers in the pharmaceutical sciences and pharmacy practice: A global perspective”, October 21-23, 2015, Amman, Jordan.
- Ghassan Abu Sheikha, Dima Sabbah, Reema Abu Khalaf, Tariq Al-Qirim, Sanaa Bardaweel; Poster Presentation: Design, Synthesis and Biological Evaluation of Novel PI3K Alpha Inhibitors with Potential Anti-Cancer Activity, Computer Aided Drug Design: New Frontiers in computer-Aided Drug Design, July 19-24, 2015, VT, USA.
- Reema Abu Khalaf, Ghassan Abu Sheikha; Oral Presentation: Potential CETP and DPP-IV Inhibitors: Design, Synthesis and Biological Evaluation, Bilateral research workshop between Faculty of Pharmacy, Al-Zaytoonah University of Jordan, and Faculty of Pharmacy, University of Szeged, Hungary, October 21, 2014, Amman, Jordan.
- Ghassan Abu Sheikha, Reema Abu Khalaf, Dima Sabbah; Poster Presentation: Design, Synthesis, and Biological Evaluation of a New Series of Potential CETP Inhibitors, Ligand Recognition & Molecular Gating: Structure and Dynamics of Ion Channels, G-Protein Coupled Receptors, and Solute Transporters, March 23-28, 2014, Ventura, CA, USA.
- Ghassan Abu Sheikha, Reema Abu Khalaf; Poster Presentation, FloHet-2013 Florida Heterocyclic and Synthetic Conference, March 3-6, 2013, Gainesville, Florida, USA.
- Ghassan Abu Sheikha, Reema Abu Khalaf, Mahmoud Al-Sha’er, Ghadeer Albadawi, Mutasem Taha; Poster Presentation: Design, synthesis and biological evaluation of aryl-succinamic, phthalamic, acrylic and acetic acid derivatives as potential DPP IV inhibitors, International Symposia on Advancing the Chemical Sciences- Challenges in Organic Chemistry and Chemical Biology (ISACS7), June 12-15, 2012, Edinburgh, UK.
- Reema Abu Khalaf; Oral Presentation: Design, Synthesis and Biological Evaluation of Sulfonic Acid Ester and Benzenesulfonamide Derivatives as Potential CETP Inhibitors, The International Conference of Young Chemists (ICYC), April 8-10, 2012, held at University of Jordan, Amman, Jordan.
- Reema Abu Khalaf; Oral Presentation: Discovery of New CETP Inhibitors via Ligand-Based Pharmacophore Modeling and QSAR Analysis and Subsequent Hit Optimization, The Jordanian International Pharmaceutical Conference 2008 (JIPC), October 15-17, 2008, held at Al-Zaytoonah University of Jordan, Amman, Jordan.
- Reema Abu Khalaf; Oral Presentation: The Synthesis and Microbiological Evaluation of Some Novel Derivatives of Some Natural and Synthetic Polymers, The Jordanian International Pharmaceutical Conference 2006 (JIPC), November 15-17, 2006, held at Al-Zaytoonah University of Jordan, Amman, Jordan.
Sunday 18, 2015
- Participate in a Training Workshop entitled: ”إعداد مقيم جودة تعليم عالي معتمد لدى الهيئة” organized by the Accreditation and Quality Assurance Commission for Higher Education Institutions, held at Princess Sumaya University for Technology, Amman, Jordan, 15-16 September 2019.
- Participate as oral presentation in the 4th Pharmaceutical Chemistry Conference held at Amsterdam, Netherlands, 27-28 June 2019.
- Participate in a Training Workshop entitled: ”Applied Advanced Statistic Assisted with SPSS Software” held at Al- Zaytoonah University of Jordan, Amman, Jordan, 18-20 February 2019.
- Participate in a Training Workshop entitled: ”براءات الاختراع” held at Al- Zaytoonah University of Jordan, Amman, Jordan, 25 September 2018.
- Participate as oral presentation in BIT’s 16th Annual Congress of International Drug Discovery Science and Technology (IDDST) held at Boston, USA, 16-19 August 2018.
- Participate in a Training Course entitled: ‘Using and Managing E-Learning System’ held at Al- Zaytoonah University of Jordan, Amman, Jordan, 1-4 October 2017.
- Participate as oral presentation in BIT’s 15th Annual Congress of International Drug Discovery Science and Technology (IDDST) held at Osaka, Japan, 25-27 July 2017.
- Participate in a Training Workshop entitled: ”التخطيط الإستراتيجي: مفهومه وإطاره الإرشادي ومراحله المختلفة” held at Al- Zaytoonah University of Jordan, Amman, Jordan, 13 June 2017.
- Participate as poster presentation in ASU- Pharmacy Third Conference and The Third Conference of the Association of Faculties of Pharmacy at Jordanian Universities entitled: “Recent Trends in Postgraduate Research” held at Faculty of Pharmacy, Applied Science University, Amman, Jordan, 15-16 April 2017.
- Participate in a Training Workshop entitled: ”ISO 9001: 2015معايير ” held at Al- Zaytoonah University of Jordan, Amman, Jordan, 12-13 April 2017.
- Participate in a 20 hours Training Workshop entitled: ‘‘ادارة الجودة الكاملة Total Quality Management’’ held at Al- Zaytoonah University of Jordan, Amman, Jordan, 5-16 February 2017.
- Participate in a Training Workshop entitled: ”تصنيف الجامعات الأردنية” held at Al- Zaytoonah University of Jordan, Amman, Jordan, 1 February 2017.
- Participate in The 3rd National Conference of Erasmus+ held at Le Royal Hotel, Amman, Jordan, 26 October 2016.
- Participate in The 4th International Conference of the School of Pharmacy-The University of Jordan and The 2nd Conference of the Association of Faculties of Pharmacy at Jordanian Universities entitled “Excellence in Pharmacy Education & Research: A Quality Approach” held at The University of Jordan, Amman, Jordan, 25-27 October 2016.
- Participate in a Training Workshop entitled: ”Bruker Biospin & Bruker Optics ” held at Days Inn Hotel, Amman, Jordan, 20 October 2016.
- Participate in a Training Workshop entitled: ”واستخداماته في تحليل بيانات الدراسات العلمية SPSS أساسيات النظام الاحصائي ” held at Al- Zaytoonah University of Jordan, Amman, Jordan, 26-29 September 2016.
- Participate in a Quality Assurance Workshop entitled: ”دليل القياس الصادر عن هيئة اعتماد مؤسسات التعليم العالي” held at Al- Zaytoonah University of Jordan, Amman, Jordan, 24 May 2016.
- Participate in a Quality Assurance Workshop entitled: ”التطبيق الخلاق لمعايير الاعتماد العام والاعتمادات الخاصة للتخصصات” held at Al- Zaytoonah University of Jordan, Amman, Jordan, 12 May 2016.
- Participate in a Quality Assurance Workshop entitled: ”القياس والفاعلية” held at Al- Zaytoonah University of Jordan, Amman, Jordan, 10 March 2016.
- Participate as poster presentation in ASU Second Symposium “Recent Trends in Postgraduate Research” held at Faculty of Pharmacy, Applied Science University, Amman, Jordan, 5-6 December 2015.
- Participate as Oral Presentation and Session Moderator in Al-Zaytoonah University of Jordan & The University of Toledo International Pharmaceutical Conference 2015 (ZTIPC) held at Al- Zaytoonah University of Jordan, Amman, Jordan, 21-23 October 2015.
- Participate in the Scientific Day of Faculty of Pharmacy entitled: ”Pharmacy Sciences and Practice: An updated perspective” held at Faculty of Pharmacy, The University of Jordan, Amman, Jordan, 29 April 2015.
- Participate as Oral Presentation in the First National Conference entitled: ”Recent Trends in Postgraduate Research” held at Faculty of Pharmacy, Applied Science University, Amman, Jordan, 20-21 December 2014.
- Participate as Oral Presentation in the Bilateral Research Workshop Between Faculty of Pharmacy, Al-Zaytoonah University of Jordan, and Faculty of Pharmacy, University of Szeged, Hungary held at Al- Zaytoonah University of Jordan, Amman, Jordan, 21 October 2014.
- Participate in the 6th Conference on Scientific Research in Jordan held at Al- Zaytoonah University of Jordan, Amman, Jordan, 23 November 2013.
- Participate in a Workshop entitled ”اعداد المقومين الخارجيين والزيارة الميدانية لاعتماد البرنامج الأكاديمي ” held at Al- Zaytoonah University of Jordan, Amman, Jordan, 2-4 November 2013.
- Participate in a Workshop entitled ”Computer-Aided Drug Design” held at Hamdi Mango Center for Scientific Research, University of Jordan, Amman, Jordan, 20 October 2013.
- Participate as Session Moderator in the Scientific Day of Cancer held at Faculty of Pharmacy, Al- Zaytoonah University of Jordan, Amman, Jordan, 15 May 2013.
- Participate in a Workshop entitled ”للتدقيق الداخلي Baldrigeاستخدام نظام ” held at Al- Zaytoonah University of Jordan, Amman, Jordan, 4 April 2013.
- Participate in a Workshop entitled ”اعداد وثيقة التقويم الذاتي للبرامج الأكاديمية” held at Al- Zaytoonah University of Jordan, Amman, Jordan, 4 April 2013.
- Participate in The 3rd International Arabic Conference of Quality Assurance in Higher Education held at Al- Zaytoonah University of Jordan, Amman, Jordan, 2-4 April 2013.
- Participate in Al-Zaytoonah University of Jordan & The University of Toledo International Pharmaceutical Conference 2012 (ZTIPC) held at Al- Zaytoonah University of Jordan, Amman, Jordan, 17-19 October 2012.
- Participate in The 15th Scientific Congress of the Association of Pharmacy Colleges in the Arab World & The 3rd International Conference of the Faculty of Pharmacy/ The University of Jordan entitled as ”RECENT TRENDS AND ADVANCES IN PHARMACY” held at University of Jordan, Amman, Jordan, 9-11 October 2012.
- Participate in The National Day of Quality Measurement & Performance Appraisal (JAQM 2012, What can’t be measured, can’t be improved), Amman, Jordan, 7 May 2012.
- Participate in the Scientific Day of Hamdi Mango Center for Scientific Research held at HMCSR/ University of Jordan, Amman, Jordan, 26 April 2012.
- Participate as Oral Presentation in The International Conference of Young Chemists (ICYC) held at University of Jordan, Amman, Jordan, 8-10 April 2012.
- Participate in The Regional Workshop on ”A Holistic Approach to achieve Quality in Higher Education” held at Landmark Hotel – Amman, Jordan, 11-12 January 2012.
- Participate in The Fifth Conference on Scientific Research in Jordan held at Landmark Hotel – Amman, Jordan, November 2011.
- Participate as Session Moderator in The Jordanian International Pharmaceutical Conference 2010 (JIPC) held at Al- Zaytoonah University of Jordan, Amman, Jordan, 20-22 October 2010.
- Participate as Oral Presentation in The Jordanian International Pharmaceutical Conference 2008 (JIPC) held at Al- Zaytoonah University of Jordan, Amman, Jordan, 15-17 October 2008.
- Participate as Oral Presentation in The Jordanian International Pharmaceutical Conference 2006 (JIPC) held at Al- Zaytoonah University of Jordan, Amman, Jordan,15-17 November 2006.
- Participate in seminar introduced by WATERS CO. representative about “ Method Validation in HPLC “ , University of Jordan, Amman, Jordan, March 2002.
- Participate in The 5th Scientific Congress of the Association of the Colleges of Pharmacy in the Arab Word & the 2nd International Conference of the Faculty of Pharmacy entitled as “New Millennium, New Horizons in Pharmaceutical Sciences“ held at University of Jordan, Amman, Jordan, 16-18 October 2001.
- Participate in a Scientific Day about “Clinical Pharmacy Practice“ held at Al-Zaytoonah University of Jordan, Amman, Jordan, Nov. 1999.
- Participate in a training course on using High Performance Liquid Chromatography/ UV/Gradient Elution Pump, at Pharmaceutical Research Unit, Royal Scientific Association, Amman, Jordan, one month 1998.