Master Thesis Abstracts for Pharmaceutical Sciences

 

Academic year 2023-2024

 Title

Researcher

Supervisor

Co-Supervisor

Date of discussion

Language of the Thesis

Abstract

1. Plasma 1H NMR-based metabolomic analysis of the lipid regulating effect of novel carboxamide derivatives in Triton WR-1339 induced hyperlipidemic rats

 Rahaf Mazen AL-Ejel

Dr. Mohammad Alwahsh

Dr. Lama Hamadneh 

16-01-2024 

English 

PDF

2. A Computational Drug Repurposing Workflow to Prioritize Pharmacotherapeutics for COVID-19 and Other Infectious Diseases

Reham Abdel Rahman Kharma

Dr. Rima Hajjo

 –

15-01-2024  

 English 

PDF

3. Fabrication and Characterization of Plant-mediated Zinc Oxide Nanoparticles Loaded into Dissolving Microneedles

 Haneen Faris Al-Shawabkeh

Prof. Rania Hamed

– 

14-01-2024  

 English 

 PDF

4. Phytochemical screening and antiproliferative activity of Varthemia montana Grown in Jordan

 Hala Ismail Abulawi

Dr. Nour Aboalhaija 

Prof. Rania Hamed

14-01-2024  

 English 

 PDF

5. Use of Combined Polymers in Microneedles Manufacture: Effect of Polymer Type and Permeation Enhancers on Thermal and Mechanical Properties

Alghadeer Haider Al Shammari

Dr. Ola Tarawneh

 –

11-01-2024  

 English 

 PDF

6. The Application of Pharmacoinformatics Approaches to Study Post COVID-19 Complications and Prioritize Drug Targets and Effective Therapeutics: A Focus on Metabolomic Disturbances and Post-COVID-19 Diabetes

Raghad Alqernaw

Dr. Rima Hajjo

 –

 10-01-2024 

 English 

 PDF

7. Preparation and Characterization of Orodispersible and Orodissolvable Polymeric Films: Effect of Polymer Type and Combination on Drug Release Rate

 Heba Sami S. Al-Ryalat

Dr. Ola Tarawneh 

 

 10-01-2024 

 English 

 PDF

8. The Application of Pharmacoinformatic Methods for the Prioritization of Drug Targets and Therapeutics for Multisystem Inflammatory Syndrome in Children (MIS-C)

Ruba Almaletti 

Dr. Rima Hajjo

– 

 09-01-2024 

 English 

 PDF

9. The Effect of Combined Polymer Types and Their Mechanical Properties on Alpha-Arbutin Dissolved Microneedles

Sara Ibrahim Almasri 

 Dr. Ola Tarawneh

– 

08-01-2024

 English 

 PDF

10. Jordanian growth references for Jordanian Children aged 3 to under 18 years compared to WHO and CDC growth Standardized National Growth Charts

Ruba Fares Zumot

 Dr. Walid Al-Qerem

 

07-01-2024

 English 

 PDF

11. Development and Biological Evaluation of a Polymeric Nanoformulation for the Bioactive Extracts of Ephedra alata L.

Riham Almughier 

 Prof. Suhair Sunoqrot

Dr. Kenza Mansoor 

 04-01-2024

 English 

 PDF

12. An Investigation of Aldehyde Dehydrogenase Enzyme as a Target for Drug Design and Potential Therapeutic Applications

Lina Talal Khalil Abdelhadi 

Dr. Ali Ibrahim 

 Dr . Rawan Huwaitat

04-01-2024

 English 

 PDF

Academic year 2022-2023

 Title

Researcher

Supervisor

Co-Supervisor

Date of discussion

Language of the Thesis

Abstract

1.Glutamate, glutamine, cystine, glutathione, and xanthine biomarkers correlation with their genes expression in Tamoxifen-resistant MCF-7 cells

 Mais Emad Altaweel

 

 

12-6-2023 

English 

PDF

2.The Association of Genetic Variants in Vitamin D Receptor (VDR) with the Severity of COVID-19 Infection, persistent Symptoms, and post-Vaccination Symptoms

Ghaida’ Khaleel Al-Hamadeen

11-6-2023 

English 

PDF

3.The impact of novel lipid-lowering drugs on the expression of inflammatory markers in Triton WR 1339 induced hyperlipidemic rats

 

Yasmeen Mahmoud “Zaid al-Kilani” 

 

11-6-2023 

English 

PDF

4.Molecular Changes Associated with Novel Carboxamide Derivatives’ Treatment of Triton WR1339 Induced Hyperlipidemic Rats.

Aya Ahmad Hasan

 

11-6-2023 

English 

PDF

5.Standardized National Growth Chart of 0-2 Years Old Jordanian Children

Lina Ahmad Bataineh

 

8-6-2023 

English 

PDF

6.Development and Evaluation of Mitoxantrone-Loaded Polyquercetin Nanoparticles and their Potential Synergism with other Anticancer Agents

Otrujja Jamal Alkhaldi 

 

8-6-2023 

English 

PDF

7.Safety Evaluation of Potential Toxic Metals Exposure from Commonly Used Omega 3 Products for Infants in Jordan

Ghada Ismail Abd Allatef Al-Azzeh  

 

8-6-2023 

English 

PDF

8.Cytokines Genotype variants on the pathogenesis of Systemic Lupus Erythematosus among Jordanian patients

Seham Fareed Zarour

 

 

7-6-2023 

English 

PDF

9. A Glucose Oxidase-Based Nanocarrier for Multimodal Synergistic Cancer Therapy

Rama Salem AlSamarat

6-6-2023 

English 

PDF

10. Synthesis, Characterization, and Biological Study of New Meta-Methylated Sulfonamide Derivatives as Inhibitors of Cholesteryl Ester Transfer Protein

Rand Moh’d A. Abuarqoub

6-6-2023 

English 

PDF

11.Comparison of cytokines relative mRNA expression in multiple sclerosis (MS) patients with a control group

Mohammed waleed Al Mosleh

5-6-2023 

English 

PDF

12.Cytotoxic Differences of Anticancer Drugs on 2D and 3D Cancer Cell Lines

Amani Mahmoud AlDoridee

4-6-2023 

English 

PDF

13.COVID-19 vaccine acceptance among pregnant, lactating and planning to conceive Jordanian women.

Yara Bassam Al-Shawabkeh

4-6-2023 

English 

PDF

14. A study of Major Histocompatibility Complex (MHC) genes’ association with Multiple Sclerosis in Jordanian patients

Lubna Ghazi Al-Khreishah

4-6-2023 

English 

PDF

15.Para-Methylated Benzene Sulfonamides as Potential CETP Inhibitors: Chemical Synthesis and In Vitro Validation

Marah Belal Afaneh

17-1-2023 

English 

PDF

16.Development and Characterization of Anticancer Model Drug Conjugated to Biosynthesized Zinc Oxide Nanoparticles Loaded into Different Topical Skin Formulation

Rawaa’ Zuhier Sakib Obeid 

 Prof. Rania Hamed

Prof. Rana Abu-Huwaij 

17-1-2023 

English 

PDF

17.Development and Characterization of Minoxidil Nanosuspension-loaded Dissolved Microneedles for Hair Regrowth

Hebah Fayiz Ibrahim Alhadidi 

 Prof. Rania Hamed

 –

 16-1-2023

English 

 PDF

18.Green Gels for Topical Delivery Prepared from Orange Peels: Investigation of the Rheology Behavior and Antimicrobial and Antioxidant Activities 

Kamar Hamdan Magamseh 

Prof. Rania Hamed 

Dr. Eveen Al-Shalabi 

15-1-2023 

English 

 PDF

19.The Effect of Diabetes Mellitus and Fasting on Gene Expression of Drug-Metabolizing Enzymes in the Livers of Mice 

Nour Marwan Ata Al-Kazimi 

 Dr. Abdullah El Madani

Dr. Yazun Jarrar 

15-1-2023 

 English

 PDF

20.Effects of Maternal Separation on the Expression of Hepatic Drug-Metabolizing Enzymes  

 Walaa Ashour

 Dr. Abdulla El Madani

Dr. Yazun Jarrar 

15-1-2023 

 English

PDF 

21.Novel Ortho-Chlorinated Benzenesulfonamides: Synthesis, Characterization and Biological Validation as Promising CETP Inhibitors

 Farah Essam Al Khawaldeh

Prof. Dr. Reema Abu Khalaf 

 –

 12-1-2023

English 

 PDF

22.Sequence Analysis of N-Acetyltransferase 2 Gene among Type II Diabetic Patients In Jordan 

Dana Yousef Zaiter 

Dr. Abdulla El Madani 

Dr. Yazun Jarrar 

 10-1-2023

English 

 PDF

23.Synthesis, Characterization, and CETP Inhibitory Potential of Novel meta-Trifluoromethylated Aromatic Sulfonamides 

Nataly Mohammed Abu Ajamieh 

Prof. Reema Abu Khalaf 

– 

 5-1-2023

English 

PDF 

24.Comparison between the inflammation status of several organs after whole body exposure with waterpipe and cigarettes smoke: In vivo study on rats 

Rasha Ramzi Debas 

Dr. Alaa M. Hammad 

Dr. Osama Abusara 

27-12-2022 

English 

 PDF

25.Knowledge, attitudes, and practices of Jordanian patients toward Self-Medication

Afnan Adnan Barghoth  

Dr. WALID ALQEREM

5-12-2022

English 

PDF  

Academic year 2021-2022

 Title

Researcher

Supervisor

Co-Supervisor

Date of discussion

Language of the Thesis

Abstract

1.Chemical and Biological Evaluation of Lavender (Lavandula angustifolia and Lavandula stoechas) Grown in Jordan

Heba Dawood Mohammed Syaj  

Dr. Nour Aboalhaija

08-2022

English 

PDF  

2.Dermal Delivery of Anti-Wrinkle Agent Using Nanoemulsions and Nanoemulsion Loaded Gels

Baraah Jihad Abu nahia 

Rania Hamed

Rana Obeidat

30-08-2022

English 

PDF  

3.Systematic Review And Meta-Analysis Of Real-World Effectiveness Of Osimertinib In
Non-Small Cell Lung Cancer (NSCLC) With EGFR Mutation

Mais Nader Maghaireh 

Dr. Nimer Alkhatib

29-08-2022

English 

PDF  

4.Risk factors associated with the need to use corticosteroids in hospitalized patients with COVID-19

Mohammed Sufian Ibrahim Safar 

Dr. Walid Al-Qerem

24-08-2022

English 

PDF  

5.Development and Optimization of Antimicrobial Nanoemulsion-loaded into Two Bigels: A Comparative Study

Wala’a Taiseer Abu Al-Ata  

Prof. Rania Hamed

24-08-2022

English 

PDF  

6.Clinical Features of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV2) COVID-19 related to Age group: A Retrospective Analysis of Symptoms, Treatments and Outcomes

Ibrahim Sufian Ibrahim Safar 

Dr. Walid Al-Qerem

22-08-2022

English 

PDF  

7.Immunogenetic profile of Lupus nephritis among Systemic Lupus Erythematosus Jordanian patients

Rawan Mohammad Bdour 

Dr. Sawsan Khdair

31-07-2022

English 

PDF  

8.Development of a Polymeric Nanomedicine to Improve the Bioactivity and Bioavailability of Plant Polyphenols

 Malak Mustafa Al-Kurdi 

Dr. Abdel Qader Al bawab

 Dr. Suhair Sunoqrot  

 07-06-2022

English 

PDF  

9.Synthesis, Characterization, and In-Vitro Validation of New MetaChlorinated Diaryl Sulfonamides as Potential Inhibitors of
Cholesteryl Ester Transfer Protein

 Ala’a Nafez Issa Lafi

Prof. Dr. Reema Abu Khalaf

– 

 06-06-2022

 English

PDF 

10. Predictors of response and secondary failure to Albiglutide therapy in type
2 diabetic patients

Saif Sami

Dr. Abdel Qader Al bawab

Dr. Mohammad Issa Saleh

 06-06-2022

English

PDF 

11. Chemical Synthesis and Biological Evaluation of Novel OrthoFluorinated Benzene Sulfonamides as Potential CETP Inhibitors

Lama Abdallah Al Jaradat  

 Prof. Dr. Reema Abu Khalaf

– 

 02-06-2022

English

PDF  

12.New Meta-Fluorinated Diaryl Sulfonamides: Synthesis and in Vitro Study as Promising Cholesteryl Ester Transfer Protein Inhibitors

Yasmin Mahmoud Selim Ibrahim  

 Prof. Dr. Reema Abu Khalaf

– 

31-05-2022 

English 

 PDF  

13.Assessment of society’s attitude towards the vaccine for the emerging
corona disease in children

Tasneem Matloub Aljabr 

Dr: Abdel Qader AlBawab

30-05-2022

English

PDF  

14.Economic Modeling For Jordan Of The Cost-Efficiency And Associated Expanded Treatment Access Of Conversion To Rituximab Biosimilar From Reference Rituximab

Hala Hisham Halawah 

Dr. Nimer Alkhatib

– 

30-05-2022 

 English

PDF   

15.Development of a Polymeric Nanoparticle Formulation for
Phosphatidylinositol 3-Kinase Alpha (PI3Kα) Inhibitors as a Potential
Anticancer Nanomedicine 

Sundos Fouad Aliyeh  

 Dr. Suhair Sunoqrot

 Dr. Dima Sabbah

19-05-2022

 English

PDF   

16. The association of cytochrome 4F2 rs210622 variation with type II diabetes and its complications

Marah Hani Khalili 

Dr. Yazun Jarrar

– 

  08-5-2022

English 

PDF    

17. The Effects of Dates (Phoenix Dactylfera L.) and Fasting on the mRNA Expression of Hepatic Drug Metabolizing Enzymes

Ruba Saeed Jaber Balasmeh

Dr. Yazun Jarrar

– 

18-01-2022

English

PDF

18. Clinical Outcomes and Characteristics of Patients Hospitalized for COVID-19 in Jordan: A Retrospective Analysis Study

Mahmood Ayad Ismael Al-Ibadah

Dr. Walid Al-Qerem

– 

18-01-2022 

English

PDF 

19. Development and Evaluation of Polyphenol Nanoparticles as a Hepatoprotective Nanomedicine Against Diclofenac-Induced Hepatotoxicity

Mohammad Aref Abu-Shalhoob

Dr. Suhair Sunoqrot

Dr. Yazun Jarrar

17-01-2022 

English

 PDF

20. Fluorinated Benzene Sulfonamides as Potential Cholesteryl Ester Transfer Protein Inhibitors: Synthesis and Subsequent in Vitro Validation

Hamza Mahmoud Al Shaiah

Prof. Reema Abu Khalaf

 –

16-01-2022 

English

 PDF

21. Design, Synthesis and Biological Evaluation of Novel Anthranilic Acid Derivatives as Anticancer Agents Targeting Tyrosine Kinases

Najah Abdallah Al-Rammouni

Dr. Ali Ibrahim

Dr. Qasem Abdallah

13-01-2022 

English

 PDF

22. Aspirin Effect on Tobacco Smoke Withdrawal-Induced Anxiety in Female Rats

Lujain Faiq Al-Zaghari

Dr. Alaa Hammad

– 

12-01-2022 

English

 PDF

23. Effects of Testosterone and Oxandrolone on the mRNA Expression of SARS2 Virus-Entery Genes in the Lung of Mice

Dana Ismail Lutfi ALNajjar

Dr. Yazun Jarrar

– 

30-12-2021 

English

 PDF

 

Academic year 2020-2021

 Title

Researcher

Supervisor

Co-Supervisor

Date of discussion

Language of the Thesis

Abstract

1. Diaryl sulfonamides: synthesis, characterization and in vitro biological evaluation as CETP inhibitors

Azhar Mohammad Salem Shalluf

Prof. Reema Abu Khalaf

– 

25-08-2021 

English

PDF 

2. Association between cytokine genes polymorphisms and diabetes in Jordanian population: a case-control study

Ola Salim Al-Naimat

Dr. Sawsan Khdair

Dr. Wassan Jarrar

 17-08-2021

English

PDF 

3. The knowledge attitude behavior of community PCPs on anticoagulant therapy for NVAF patients

Diyar Hameed Ali

Dr. Walid Al-Qerem

– 

26-05-2021 

English

PDF 

4. Preparation and Characterization of Rhoifolin-Loaded Polymeric Nanoparticles as a Potential Natural Nanomedicine for inflammation

Samah Maher Abusulieh

Dr. Suhair Sunoqrot

Dr. Eveen Al-Shalabi

 26-05-2021

English

 PDF

5. Design, Synthesis, and Biological Evaluation of Nitrated N-Substituted-4-Hydroxy -2-Quinolone-3-Carboxamides as PI3Kα Inhibitors

Reem Ahmad Ismael Isleem

Dr. Dima A. Sabbah

Prof. Reema Abu Khalaf

24-05-2021 

English

PDF 

6. Design, Synthesis, and Biological Evaluation of N’-(Diphenylmethylene) Benzohydrazide Derivatives as PI3Kα Inhibitors

Qutaiba Salah Jasim

 Dr. Dima A. Sabbah

– 

23-05-2021 

English

PDF 

7. The Influence of Non-Steroidal Anti-Inflammatory Drugs and Paracetamol on the Expression of the Lung Coronavirus (COVID-19) Attachment Receptor and Enzyme Genes in Mice

Fatima Nasr Ahmad Khirfan

Prof. Tariq Al-Qirim

Dr. Yazun Jarrar

23-05-2021 

English

 PDF

8. Synthesis and Biological Evaluation of Aromatic Sulfonamides as Novel Cholesteryl Ester Transfer Protein Inhibitors

Manal Jamal As’ad

Prof. Reema Abu Khalaf

 –

20-05-2021 

English

PDF 

9. Creating a Deep Learning Model to Predict off-target DNA sites using prime editing technique

Khaled Mohammad Ahmad Jum’ah

Dr. Lama Hamadneh

Dr. Krzysztof Poterlowicz

 20-05-2021

English

PDF 

10. Optimization of N-Substituted-6-Chloro-4-Hydroxy-2-Quinolone-3-Carboxamides as PI3Kα Inhibitors

Sara JamalEddin Meknas

Dr. Dima A. Sabbah

Dr. Eveen F. Shalabi

19-10-2021

English

PDF

11. Design, Synthesis, and Biological Evaluation of N-Substituted-7-Methyl-4-Hydroxy-2-Quinolone-3-Carboxamides as PI3Kα Inhibitors

Batool Mohammed Al-lahowani

Dr. Dima A. Sabbah

Dr. Rima Hajjo

18-01-2021 

English

PDF 

12. Evaluation of Compounding Practices that Increases the Risk of Microbial Spoilage of Pharmaceutical Products in Jordanian Community Pharmacies

Rafeef Abd Alrhman Maharmah

Dr. Mohammad Abu Sini

Dr. Mohammad Al-Sabi

 18-01-2021

English

 PDF

13. The Effect of Diabetes and its Management: Insight on Costs and Quality of Life from Jordan

Mohammad Abdulghani Badinjki

Dr. Walid Al-Qerem

– 

 18-01-2021

English

 PDF

14. Development and Characterization of Biomaterials Used in Urinary Catheters to Minimize Microbial Adherence

Hadeel Abdel all Abu Mahfouz

Dr. Ola Tarawneh

Dr. Ahmad Deeb

17-01-2021 

English

PDF 

15. Fabrication, Characterization, and Biological Evaluation of Coal Tar-Encapsulated Polymeric Nanoparticles for Psoriasis Treatment

Mohammad Niazi Yasin

Dr. Suhair Sunoqrot

Dr. Luay Abu-Qatouseh

14-01-2021 

English

PDF 

16. Protective Effect of Metformin on Oxandrolone-Induced Neuroinflammation and Behavioral Changes in Rats

Yasmeen Al Haytham Ibrahim

Dr. Alaa Hammad

Dr. Sawsan Khdair

 04-01-2021

English

PDF 

 

Academic year 2019-2020

 Title

Researcher

Supervisor

Co-Supervisor

Date of discussion

Language of the Thesis

Abstract

1. Validating the Applicability of GLI 2012 Equations on the Iraqi Adults

Alaa Hussein Abdullah alsajri

Dr. Waleed Al-Qirim

 –

26-08-2020

English 

PDF 

2. Tamoxifen Resistance in MCF-7: Tracking the Changes in PI3K/ AKT/ PTEN Signaling Pathway and Their Role in Glucose and Glutamine Metabolism During Resistance Development

Rama Moh’d A. Abuarqoub

Dr. Lama Hamadneh

Dr. Ala Alhusban

26-08-2020

English 

 PDF

3. Development and Evaluation of Curcumin-loaded Tannic Acid Nanoparticles as an Anti-cancer Nanomedicine

Bayan Jamal Al-Orainee

Dr. Suhair Sunoqrot

– 

26-08-2020

English 

PDF 

4. Synthesis, Characterization and Biological Evaluation of Novel Fluorinated Oxoacetamido Benzamides as Potential CETP Inhibitors

Mohammad Khalel Mohammad Awad

Prof. Reema Abu Khalaf

Prof. Tariq Al-Qirim

25-08-2020

English 

 PDF

5. Tamoxifen Resistance and its Role in Migration and Invasion of an in Vitro Cell Line Model at the Molecular Level

Mohamad Haitham Bahader

Dr. Lama Hamadneh

25-08-2020

English 

 PDF

6. Development of Biomaterial Used in Urinary Catheters to Prevent Microbial Adhesion: Effect of Drug type

Wasan Ibraheem Al-wahsh

Dr. Ola Tarawneh

Dr. Hassan Abul-Futouh

25-08-2020

English 

PDF 

7. Chromatographic and/or Electrophoretic Methods Development and Validation for Correlating Tamoxifen Resistant MCF-7 Cell Line Changes With Biomarkers (Lactate, Pyruvate, glucose and Glutamine) Level

Sokiyna Mohammed Ahmed Albustanji

Dr. Ala Alhusban

Dr. Lama Hamadneh

24-08-2020

English 

 PDF

8. Antioxidant Activity and Protective Effect of Fluoroquinolones Derivatives in Carbon Tetrachloride induced Liver Injury in Rats

Manal Abdel Rauf Hussein Suleiman

Prof. Tariq Al-Qirim

Prof. Yusuf Mohammad Al-Hiari

23-08-2020

English

 PDF

9. Effects of Waterpipe Whole Body Exposure on Gene Expression of Glial Glutamatergic Transporters in Different Misocorticolimbic Brain Regions

Ghadeer “Mohammad Saeed” Swiss

Dr. Alaa Mahmoud Hammad

 –

13-08-2020

English

 PDF

10. The Association of Soluble Epoxide Hydrolase Genetic Variants with Hypertensive Diabetic Patients Type II

Maysoon Mohammed Khamees

Prof. Tariq Al-Qirim

Dr. Yazun Jarrar

06-08-2020

English

 PDF

11. Nanofibers Material as a Potential Dressing of Wound: Development and Characterization

Haneen Ahmad Qapooq

Dr. Nouf Nawaf Mahmoud

 Prof. Rana M. Abu-Dahab

27-07-2020

English

 PDF

12. In Vitro Anti-Invasion of Surface Modified Gold Nanorods Against Prostate Cancer

Hakam Mohammad Saleh Al-aqabani

Dr. Nouf Nawaf Mahmoud

Prof. Rana M. Abu-Dahab

Dr. Suhair Hikmat Jasim

10-06-2020

English

PDF 

13. The Molecular Protective Mechanism of Metformin Against Oxandrolone-Induced Mood Depression and Infertility in Rats

Abdulqader Fadhil Abed

Dr. Yazun Bashir Jarrar

– 

09-06-2020

English

 PDF

14. Doping in Jordanian population: analytical cross-sectional study

Haneen Mohammad Younis Tailakh

Dr. Abdel Qader AL Bawab

Dr. Mohanad Odeh

08-06-2020

English

PDF 

15. Pharmaceutical innovation in Jordan: where are we on the map?

Rami Tayseer Mohammad Amer

Dr. Abdel Qader AL Bawab

– 

08-06-2020

English

 PDF

16. Antihyperlipidemic Effects of Carboxamides Derivatives in Triton-WR-1339 Induced Hyperlipidemia in Rats

Hanan Fares Abdulrahman Al-Ashqer

Prof. Tariq Musbah Al Qirim

– 

04-06-2020

English

 PDF

17. Chlorinated Derivatives of N-Substituted-4-Hydroxy-2-Quinolone-3-Carboxamides as P13Kα inhibitors

Rawan Amer Haroon 

Dr. Dima A. Sabbah

– 

15-01-2020

English

 PDF

18. Schiff’s Bases: Synthesis, Characterization, In Vitro and In Vivo Biological Evaluation as DPP-IV Inhibitors

Maha “Jamil Ibrahim” Mahmoud Awad

Prof. Reema Abu Khalaf 

Dr. Luay Al-Essa

24-12-2019

English

PDF

19. Halogenated Benzamides: Synthesis and In Vitro Study as Potential Cholesteryl Ester Transfer Protein (CETP) Inhibitors

Bara’a Sameeh Hasan Al-Nawaiseh

Prof. Reema Abu Khalaf 

22-12-2019

English

PDF

 

Academic year 2018-2019

 Title

Researcher

Supervisor

Co-Supervisor

Date of discussion

Language of the Thesis

Abstract

1. Penetration of Gold Nanoparticles Through Blood Brain Barrier and their Accumulation into The Brain: Effect of Nanoparticles’ Shape and Surface Chemistry

Abdulrahim Mohamad Albasha

Dr. Nouf Nawaf Mahmoud

Dr. Suhair Hikmat Jasim

26-08-2019

English

PDF

2. In vitro characterization of model drugs (Aspirin and Candesartan Clexetile): Comparison between simulated physiologic conditions and pharmacopeial requirements

Rana Hassan Sejare

Dr. Ola Tarawneh

Dr. Samah Ata

 26-08-2019

English

PDF

3. Development and Characterization of Different Formulations of Controlled-Release Lipid-based Delivery Systems of Carvedilol

 Bayan Yaser Seder

Dr. Rania “Ahmad Azzam” Hamed

– 

 18-08-2019

English

PDF 

4. The Manufacture and Characterisation of Microbicide Medical Platforms for Oral Infections

Amal Yousef Mousa Bargash

Dr. Ola Tarawneh

Dr. Ala Alhusban  

08-08-2019 

English

 PDF

5. Development of a Polymeric Nanoformulation for Cirsiliol Isolated from Teucrium polium L.

 Muzn Jamal Alkhaldi

Dr. Suhair Sunoqrot

Dr. Eveen Al-Shalabi  

04-08-2019 

English

PDF 

6. Co-delivery of Riboflavin Immediate-Release Granules and Topiramate Extended-release Pellets: Toward Reducing the Frequency of Migraine Attack

Dua’a Omar

Dr. Rania “Ahmad Azzam” Hamed

– 

04-08-2019 

English

PDF 

7. Pharmacodynamic modeling of Glibenclamide-induced changes in hemoglobin A1C in type2 diabetic patients

 Mohannad Hussein Fayez abu dobay

Dr. Abdel Qader Al Bawab

Dr. Mohammad Issa Saleh

23-05-2019 

English

PDF 

8. Validating a tool to measure HRQOL in diabetic Jordanians

Buthaina M. Al-Maayah

Dr. Walid A. Al-Qerem

 –

22-05-2019 

English

PDF 

9. Synthesis, Characterization and Biological Evaluation of Novel Benzamides as CETP Inhibitors

Amani Ahmed Abu Saad

Prof. Reema Abu Khalaf 

– 

21-05-2019 

English

PDF 

10. Methoxylated Derivatives of N-Substituted-4-Hydroxy-2-Quinolone-3-Carboxamides as PI3Kα Inhibitors

Abdullah Mousa Abdel Fattah Abdullah

Dr. Dima A. Sabbah

Prof. Ghassan M. Abu Sheikha 

19-05-2019 

English

PDF 

11. Synthesis and Biological Evaluation of N-Substituted-4-Hydroxy-8-Methyl-2-Quinolone-3-Carboxamide Derivatives as PI3Kα Inhibitors

Tahrer Fadhil Abd AL-Bo Aswad

Dr. Dima A. Sabbah

Prof. Ghassan M. Abu Sheikha 

16-05-2019 

English

 PDF

12. Design, Synthesis, and Biological Evaluation of N-Substituted-4-Hydroxy-8-Methoxy-2-Quinolone-3-Carboxamides as PI3Kα Inhibitors

Asma Ali Jumah

Dr. Dima A. Sabbah

– 

15-05-2019 

English

 PDF

13. Development of Dual–release Pellets of the non-Steroidal Anti–inflammatory Drug Celecoxib

Haitham Omran

 Dr. Rania  Hamed

– 

09-05-2019 

English

 PDF

14. Piperazine Sulfonamides: Synthesis, Characterization, and In Vitro Biological Evaluation as Potential DPP-IV Inhibitors

Ebtisam Abdulkareem Ali Alwarafi

Prof. Reema Abu Khalaf 

 –

 09-05-2019

English

PDF 

15. Disease Progression Model To Describe Longitudinal Change In Hemoglobin A1C In Response To Gliclazide Therapy In Type2 Diabetic Patients.

Anwar Abdel Qader Hindi Jaffal

Dr. Abdel Qader Al Bawab

Dr. Mohammad Issa Saleh

01-05-2019 

English

PDF 

16. Synthesis and Evaluation of Curcumin-loaded Polyphenol Nanoparticles as a Potential Anti cancer Nanomedicine

Tahany “Mohammad Tayseer” Ahmad Al Debsi

Dr. Suhair Sunoqrot

– 

11-03-2019 

English

 PDF

17. Novel Gold Nanocomposite for Wounds Healing in Rats: Effect of Nanoparticles’ Shape and Surface Chemistry

Duaa Suleiman Abu Ghith

 Dr. Nouf Nawaf Mahmoud

Dr. Suhair Hikmat Jasim

16-01-2019 

English

PDF 

18. Synthesis and Biological Evaluation of Novel Hydrazone Derivatives as Potential DPP-4 Inhibitors

Sara Mousa Saleh Mefleh

 Prof. Reema Abu Khalaf 

Dr. Luay Al-Essa

16-01-2019 

English

PDF 

19. Ibuprofen Nanoemulsion In Situ Gel for Mucosal Adhesion in Periodontitis

Yasmeen Al-Adhami

  Dr. Rania  Hamed

– 

 14-01-2019

English

 PDF

20. Design, Synthesis, and Biological Evaluation of Fluorinated N-Substituted-4-Hydroxy-2-Quinolone-3-Carboxamides as PI3Kα Inhibitors

Hla Hasan Samarat

Dr. Dima A. Sabbah

 Dr. Eveen Al-Shalabi  

08-01-2019 

English

 PDF

21. Design, Synthesis, and Biological Evaluation of Benzophenone Hydrazone Derivatives as PI3Kα Inhibitors

Bara’a Ahmad Al-Azaideh

Dr. Dima A. Sabbah

 Prof. Ghassan M. Abu Sheikha 

06-01-2019 

English

PDF 

22. Synthesis, spectroscopic characterization and biological evaluation of phenanthridine derivatives as potential DPP-IV Inhibitors

Maram Abdallah Aburezeq

  Prof. Reema Abu Khalaf 

– 

 20-12-2018

English

 PDF

Academic year 2017-2018

 Title

Researcher

Supervisor

Co-Supervisor

Date of discussion

Language of the Thesis

Abstract

1. The Nudix Hydrolase (NUDT15) Gene Variants among Jordanian Population

Maria Osama El-Ghishan

Dr. Yazun Jarrar

06-08-2018

English

 PDF

2. Controlled–release Formulations of Carvedilol–loaded Oleogels

Hala Al-Qawass 

Dr. Rania Hamed 

– 

06-08-2018

English

PDF 

3. Tamoxifen Resistance in Breast Cancer Tracking the Changes in Lactate Dehydrogenase Gene Expression

 Lara Imad Al-Lakkis

Dr. Lama Hamadneh 

Dr. Abdel Qader Al-Bawab 

05-08-2018

English

 PDF

4. Aspects of improving quality of life in Jordanian patients with Chronic diseases: a cross sectional study

 Maha Mansour

 Dr. Abdel Qader Al Bawab

Dr. Walid Al Qerem 

02-08-2018

English

PDF 

5. Synthesis and Biological Evaluation of Sulfonamide Derivatives as New DPP-IV Inhibitors

Shorooq Abdel-Qader Alqazaqi 

 Dr. Reema Abu Khalaf 

Prof. Ghassan Abu Sheikha 

02-08-2018

English

PDF 

6. Neurotoxic Effect of Paracetamol on Female Rats: Role of Antioxidant Treatment and Prevention

Bara’a Suhail Mousa Shawaqfeh 

Prof. Tariq Musbah Al-Qirim 

Dr. Suhair Hikmat Jasim 

10-07-2018

English

 PDF

7. Synthesis and Biological Evaluation of Piperazine Derivatives as DPP-IV Inhibitors

Haya Hassan Abu Jarad 

 Dr. Reema Abu Khalaf 

Prof. Tariq Al-Qirim 

23-05-2018

English

PDF 

8. Alterations in the Gene Expression of Drug Metabolizing Enzymes in Diabetic Animal Models

Abdul Hasib Samir Kilani 

Dr. Yazun Bashir Jarrar 

Dr. Louy Youssif Al-Essa 

15-05-2018

English

 PDF

9. Development of Quercetin-loaded Polymeric Nanoparticles for Targeted Delivery to Colon Cancer

Lujain Ibrahim Abu-Jamous 

Dr. Suhair Sunoqrot 

– 

15-05-2018

English

 PDF

10. Nanoemulsion-based Oleogel Formulation of Lidocaine for Topical Delivery

Ahmad Farhan 

Dr. Rania Hamed 

 –

30-04-2018

English

 PDF

11. Bioavailability of Fluoroquinolones in Human Aqueous Humor

 Sanabel Omar Dawabsheh

Dr. Ola Tarawneh

 –

29-04-2018

English

 PDF

12. Molecular Characterization of the Antihyperlipidemic Activity of Novel Nicotinic Acid-Carboxamides Derivatives Using Rats Animal Model

Marwa Mahmoud Yousef Jwaifel 

Prof. Tariq Musbah Al-Qirim 

Dr. Suhair Hikmat Jasim  

11-01-2018

English

PDF 

13. Dissolution Behavior of the Poorly Soluble Weak Acid Drug Valsartan upon Entry in the Small Intestine

Sabreen Hasan Alnadi 

Dr. Rania Hamed 

– 

11-01-2018

English

PDF 

14. Design, Synthesis, and Biological Evaluation of N-Substituted-4-Hydroxy-6-Methyl-2-Quinolone-3-Carboxamides as PI3Kα Inhibitors

 Shaima’ Emad Hasan

Dr. Dima A. Sabbah 

 Dr. Reema Abu Khalaf 

07-01-2018

English

PDF 

15. Molecular and Metabolic Signatures Associated with Acute Paracetamol Multiple Doses Toxicity in Mice

 Mohammad Ibrahim Al-Wahsh

Dr. Lama Hamadneh 

Dr. Seddik Hammad

Dr. Roland Hergenröder 

05-11-2017

English

PDF 

 

Academic year 2016-2017

 Title

Researcher

Supervisor

Co-Supervisor

Date of discussion

Language of the Thesis

Abstract

1. Mapping the Intensive Care Unit Environment and Health Care Workers for Methicillin-Resistant Staphylococcus aureus Bacteria at Jamil Tutanji hospital, Jordan

Mohammad Hasan Abunaja

Dr. Luay Y. M. Al-Essa

31-05-2017

English

PDF

2. Identification of Novel Genetic Variant on N-Acetyltransferase 2 Gene (NAT2) with In Silico Functionality among Jordanian Population

Ayat Ahmed Issa Balasmeh 

Dr. Yazun Jarrar 

Dr. Wassan Jarrar 

24-05-2017 

English

PDF 

3. Optimization of 4-Hydroxy-2-Quinolone-3-Carboxamide Core Nucleus Targeting PI3Kα Inhibition

 Nisreen Shaban Hamadeh

 Dr. Dima A. Sabbah

Dr. Reema Abu Khalaf 

23-05-2017 

English

PDF 

4. Synthesis and Biological Evaluation of Substituted Benzylamino Benzamide Derivatives as Potential CETP Inhibitors

 Areej Khaleel Mohammad NasrAllah

Dr. Reema Abdelkareem Abu Khalaf 

Dr. Wassan Ghaleb Jarrar 

21-05-2017 

English

 PDF

5. Biological evaluation of the antimicrobial and antihyperlipidemic activity of novel 3,5 disubstitutedamido -1,2,4-thiadiazole and 2,5-disubstitutedamido -1,3,4-thiadiazole

 Luma Adel Abd Al-Samad

Dr. Lama Hamadneh 

Prof. Tariq Al-Qirim 

 10-01-2017

English

PDF 

6. Development and Optimization of Hydrogels, Oleogels, and Bigels as Topical Drug Delivery Systems for Periodontitis

Ala’a AbuRezeq 

Dr. Rania Hamed 

Dr. Ola Tarawneh 

09-01-2017 

English

 PDF

 

Academic year 2015-2016

 Title

Researcher

Supervisor

Co-Supervisor

Date of discussion

Language of the Thesis

Abstract

1. Design, Synthesis and In Vivo Biological Evaluation of Novel Benzimidazole-2-carboxamide Derivatives as Antihyperlipidemic Agents

Hanin Mohammad K. Kalloush

Prof. Ghassan Abu Sheikha

Prof. Tariq Al-Qirim 

31-08-2016

English

PDF

2. Design, Synthesis and In Vivo Biological Evaluation of Imidazole-5-
Carboxamide Derivatives as Lipoprotein Lipase Activators

 Haneen Muneer Abuzaid

Prof. Ghassan Abu Sheikha

Dr. Suhair Hikmat Jasim 

29-08-2016 

English

 PDF

3. Influence of Polymer Type and Its Molecular Weight on the Release of
Quercetin from Polymeric micelles

Aya Sadat Taha Alsadi 

Dr. Suhair Sunoqrot 

Dr. Ola Tarawneh 

18-07-2016 

English

 PDF

4. DNA Methylation Levels and the Effect on Gene Expression of Several
Genes Involved in Breast Cancer Using PCR Array

 May Mohammad Salem Al-Majawleh

Dr. Lama Hamadneh 

Dr. Yazun Jarrar 

06-06-2016 

English

 PDF

5. Optimization and Synthesis of Benzoin Derivatives as PI3Kα Inhibitors

Ameerah Said Mahmoud (Hasan Ibrahim) 

Dr. Dima Azzam Sabbah 

Prof. Ghassan Abu Sheikha

05-06-2016 

English

PDF 

6. Synthesis of some new amide derivatives containing heterocyclic moieties such as Thiazolidinone and Azetidinone and study some of their expected antimicrobial activity

 Yasmeen Azmi El Shennawi

 Dr. Luay Al-Essa

Dr. Eveen Al-Shalabi 

31-05-2016 

English

PDF 

7. Design, Synthesis and Biological Evaluation of Benzoin Schiff’s Bases as Antitumor Agents

Fatima Mahmoud Al-Tarawneh 

Prof. Ghassan Abu Sheikha

Dr. Dima Azzam Sabbah 

23-05-2016 

English

PDF 

8. Phenanthridines: Design, Synthesis and Biological Evaluation as Potential DPP-IV Inhibitors

Dalal Yousef Al Masalha 

Dr. Reema Abu Khalaf 

Dr. Dima Azzam Sabbah 

25-04-2016 

English

 PDF

9. The Effect of pH and Ionic Strength of the Dissolution Media on the Rate of Drug Release from Matrix Tablets

 Reem Ahmad Mahir Ahmad Aljanabi

Dr. Rania Hamed 

Dr. Suhair Sunoqrot 

28-03-2016 

English

 PDF

10. Molecular Characterization of the Antihyperlipidemic Activity of Novel Indole-Carboxamides Series in Rats

Nisrin Azmy Mohamed El-Shennawy 

 Dr. Lama Hamadneh

Dr. LuayAl-Essa 

24-01-2016 

English

PDF 

11. Fluorinated Benzamine’s: Design, Synthesis And Biological Evaluation as Potential CETP Inhibitors

Sarah Mohammad Ahmad Al-Rawashdeh 

Dr. Reema Abu Khalaf 

Prof. Ghassan Abu Sheikha

20-01-2016 

English

PDF 

12. Synthesis and Antihyperlipidemic Properties of Novel N-(4-Benzoylphenyl) Pyrrole-2-Carboxamide Derivatives

 Nisreen Nazmi Haj Ahmad

 Prof. Tariq Musbah Al-Qirim

Dr. Abdel Qader Fares Al Bawab 

18-01-2016 

English

PDF 

13. Synthesis and Biological Evaluation of Novel 5-Bromo Indole-2-Carboxamide Derivatives

 Amneh Mahmoud Abu Al-Inin

 Prof. Tariq Musbah Al-Qirim

Dr. Suhair Hikmat Jasim  

31-12-2015 

English

 PDF

 

Academic year 2014-2015

 Title

Researcher

Supervisor

Co-Supervisor

Date of discussion

Language of the Thesis

Abstract

1. Distribution of Breast Cancer Molecular Subtypes among Jordanian
Patients

Ameerah Abed Al Qader Hamed Alfraihat

Dr. Lama Hamadneh

31-08-2015

English

PDF

2. Development and Optimization of Diethylamine Nanoemulsion-Based Gel Formulation

Marwa Basil Al-Zabin

Dr. Rania Hamed 

Dr. Suhair Sunoqrot 

06-08-2015

English

 

3. Synthesis and Biological Evaluation of Novel Nbenzoylphenyl-2-Furamide Derivatives

Dania Mohammed Nazer Alkabbani 

 Dr. Tariq Musbah Al-Qirim

Dr. Suhair Hikmat Jasim  

27-05-2015 

English

PDF 

4. The Effect of Polymer Type, Ratio and Viscosity Grade on the in Vitro Release of Quetiapine Fumarate Matrix Tablets

Ali Mahmoud Jasim AL-Samydai 

Dr. Rania Hamed 

Dr. Ola Tarawneh 

24-05-2015 

English

 PDF

5. Synthesis and Biological Evaluation of Substituted Fluorinated Alkyloxy Benzylamino Benzamide as Potential CETP Inhibitors

Hamada Mansour Abd El-Aal Abd El-Aziz 

Dr. Reema Abu Khalaf 

Prof. Ghassan Abu Sheikha

21-05-2015 

English

 PDF

6. Physiologically-Relevant Dissolution Media for BCS Class II Drugs: Towards Accurately Predicting the In Vivo Performance

Areeg Mohammad AwadAllah 

Dr. Rania “Ahmad Azzam” Hamed 

 –

 28-12-2014

English

 PDF

7. Pharmacophore-Based Screening and Identification of Novel Phosphoinositide 3-Kinase (PI3Kα) Inhibitors

 Musaab Mahmoud Saada

Dr. Dima Azzam Sabbah 

Dr. Reema Abu Khalaf 

15-12-2014 

English

 PDF

8. Design, Synthesis and Biological Evaluation of Novel Pi3k Alpha Inhibitors

Bayan Salah Hishmah 

Dr. Dima Azzam Sabbah 

Prof. Ghassan Abu Sheikha

01-12-2014 

English

 PDF

 

Academic year 2013-2014

 Title

Researcher

Supervisor

Co-Supervisor

Date of discussion

Language of the Thesis

Abstract

1. Design, Synthesis and Biological Evaluation of a New Series of Potential DPP-IV Inhibitors

Zainab Ali Jarekji

Dr. Reema Abdelkareem Abu Khalaf

Dr. Tariq Musbah Al Qirim

10-10-2013

English

PDF

 

Academic year 2012-2013

 Title

Researcher

Supervisor

Co-Supervisor

Date of discussion

Language of the Thesis

Abstract

1. In VIVO Antihyperlipidemic Properties of Novel Pyrrole-2-Carboxamide Derivatives in Triton Wr-1339 Induced Hyperlipidemic Rats

Rawan Aref Huwaitat

Dr. Ghassan F. Shattat

Prof. Ghassan M. Abu Sheikha

19-08-2013

English

PDF

2. Design, Synthesis and Biological Evaluation of a New Series of Potential CETP Inhibitors

 Mohamed Galal Saad El Hendy

Prof. Ghassan M. Abu Sheikha

Dr. Reema Abdelkareem Abu Khalaf

 18-08-2013

English

PDF 

3. Pharmacological Evaluation of Novel Furan-2-Carboxamide Derivatives As Antihyperlipidemic Agents in Triton Induced Rats

 Nadeem Zuhair Alhusaini

Dr. Tariq M. Al-Qirim 

Dr. Ghassan F. Shattat

06-08-2013 

English

PDF